Hi. I'm Skyler.
And I love bacteria.

Bioinformatics Consultant · M.Sc. Genome Science & Technology

Scroll down to find my contact info.

Check out my work in Nature Microbiology

About

Skyler Friedline

My career as a scientist was launched into motion at my 5th birthday when I received my first lab coat. After studying Biochemistry and Molecular Biology at UC Santa Barbara and working as an EMT, I discovered that my highest priority is preserving the environment on our planet and that microbes will be key to this goal.

My path has taken me from biotech startups to research labs at top universities, to earning an M.Sc. in Genome Science and Technology at UBC. My thesis work, which uncovered the hidden metabolic roles of rare microorganisms in anaerobic communities, was published in Nature Microbiology in 2025.

I now work as a bioinformatics consultant at Koonkie, building computational pipelines and tools for processing large-scale microbiome datasets.

My pronouns are he/him

The journey so far

2012 – 2016
University of California, Santa Barbara

B.Sc. Biochemistry & Molecular Biology

2016 – 2018
Serimmune

Research associate at an early-stage immunology startup

Focus on automation and scale-up of bacterial culturing and serum screening

2019 – 2020
University of California, Berkeley

Lab manager & research associate in Adam Arkin's Lab

Focus on microbial biotechnology for life support in deep space at CUBES

2021 – 2023
University of British Columbia · Graduate Student

M.Sc. Genome Science & Technology

Advised by Profs. Ryan Ziels and Steven Hallam

Focus on metaproteomics of anaerobic microbial communities

2023 – 2025
University of British Columbia · Research Assistant

Continuing M.Sc. thesis work in Ryan Ziels' Lab

Focus on microbial bioinformatics and data presentation

2024 – present
Koonkie Canada

Bioinformatician at a bespoke consulting firm

Focus on microbiome and biodiverisity data analysis and building computational pipelines

Outside of the lab or away from the computer, I am eager to get outside. It is our beautiful planet that inspires my work, after all. British Columbia is a playground and I split my time between backpacking, skiing, surfing, kitesurfing, bike touring, tie-dyeing, and laying motionless on the beach.

Publications

Eliminating genes for a two-component system increases PHB productivity in Cupriavidus basilensis 4G11

Sander K, Abel AJ, Friedline S, Sharpless W, Skerker J, Deutschbauer A, Clark DS, Arkin AP

Biotechnology and Bioengineering 121, 139–156 (2023)

Acetaminophen production in the edible, filamentous cyanobacterium Arthrospira platensis

Hilzinger JM, Friedline S, Sivanandan D, Cheng Y, Yamazaki S, Clark DS, Skerker JM, Arkin AP

Biotechnology and Bioengineering 122, 44–52 (2025)

Production of PHB From CO2-Derived Acetate With Minimal Processing Assessed for Space Biomanufacturing

Cestellos-Blanco S*, Friedline S*, Sander KB, Abel AJ, Kim JM, Clark DS, Arkin AP, Yang P

Frontiers in Microbiology 12, 700010 (2021) · * co-first authors

Towards a Biomanufactory on Mars

Berliner AJ, Hilzinger JM, Abel AJ, et al.

Frontiers in Astronomy and Space Science 8, 711550 (2021)

Blueprint for a pop-up SARS-CoV-2 testing lab

IGI Testing Consortium, Doudna JA, Green R, Hockemeyer D, Urnov FD

Nature Biotechnology 38, 791–797 (2020)

Interests

Biodiversity Monitoring with eDNA Environmental Biotechnology Microbial Ecology Metagenomics Metaproteomics Bioinformatics Waste Valorization Circular Economy

Connect

Feel free to reach out with questions about my work or ideas for collaboration. I love to talk about all things environmental biotechnology and accessible science.